Indoor air quality can be affected by indoor sources, ventilation, decay and outdoor levels. Although technologies exist to measure these factors, direct measurements are often difficult. Toluene and nitrogen dioxide (NO2) concentrations of residential indoor and outdoor were simultaneously measured and compared in 16 houses, using passive samplers during every 3 days for 60 days. Concentrations of toluene and NO2 were analyzed by gas chromatography and spectrophotometer, respectively. Using a mass balance model, penetration factor (ventilation rate divided by sum of ventilation rate and deposition constant) and source generation factor (source generation rate divided by sum of ventilation rate and deposition constant) were calculated by multiple indoor and outdoor measurements. The mean contributions of toluene of indoor and outdoor sources on residential indoor air quality were estimated to be 31.01% and 67.00%, respectively. On the other hand, mean contributions of NO2 were 58.93% and 41.06%, respectively. These results could be explained that contributions of indoor and outdoor air pollutants sources are different to residential indoor air concentrations. In conclusion, contributions of outdoor air and indoor sources affecting indoor air quality were effectively characterized using multiple indoor and outdoor measurements. Keywords：Contribution, Indoor air quality, Toluene, NO2