The purpose of this study was to assess an alternative method to characterize indoor environmental factors by multiple indoor and outdoor measurements. Using a mass balance model and regression analysis, penetration factor and source strength factor were calculated using multiple indoor and outdoor measurements. This study was performed in 30 selected apartments in Seoul, Asan, and Daegu area which were constructed within 4 years and over 4 years, to measure the concentration of NO2 from July, 2004 to September. The results of this study are as follows. The average concentration of NO2 in Seoul, Asan, and Daegu area in the apartment constructed within 4 years are nitrogen dioxide 48.01㎍/㎥ and in the apartment over 4 years are nitrogen dioxide 46.54㎍/㎥. Mean ratios of indoor to outdoor NO2 concentrations are Seoul 0.99, Asan 0.83, Daegu 1.18. The deposition constant and the source strength of NO2 were 0.97±0.55 hr-1 and 16.33±12.30 ppb/h, respectively. In conclusion, indoor environmental factors were effectively characterized by this method using multiple indoor and outdoor measurements. Keywords：NO2, Deposition Constant, Source strength