In this study, an enthalpy exchanger was coated by silver nano particles via spark discharge method and its antimicrobial and heat exchange efficiencies were evaluated. A method utilizing thermophoretic force was used to improve coating efficiency. Four spark discharge systems were parallel connected and generated silver nano aerosol particles (number concentration of 1.65×108 particles/cc, mode diameter of 31 nm). The coating efficiency was evaluated according to various face velocities (V=0.25~1 m/s) and temperature gradients ((Thot-Tcold)/Thot=0~0.09). The maximum coating efficiency was 90.8 % when the face velocity was 0.25 m/s and the temperature gradient was 0.09 (Thot=30 ℃, Tcold=2 ℃). Silver nano particles were coated onto the enthalpy exchange element and two different coating amounts of silver nano particles (0.11 ㎍/㎠, 0.22 ㎍/㎠) were tested. For evaluation of antimicrobial efficiency, the suspension test method with E. coli was used. After the suspension test method, CFU(colony forming unit)s of each test sample were counted and colony ratio was calculated. The colony ratio was decreased more quickly when the amount of coated silver particles was increased. When the contact time between each sample and suspension was over 3 hours, antimicrobial efficiencies of coated samples were more over 99.9 % for both amount of silver nano particle(0.11 ㎍/㎠, 0.22 ㎍/㎠). The coating of silver nano particles did not affect the heat exchange efficiency. Keywords : Enthalpy exchanger, Spark discharge system, Thermophoretic force, Antimicrobial